If the version of your using reshade is 3.1.0 or greater, change these setting in ReShade.ini(or d3d9.ini, dxgi.ini, d3d11.ini, opengl32.ini)
[GENERAL]
NoReloadOnInit=1
If you need more information, see first post of this topic.
reshade.me/forum/releases/3744-3-1