I'm playing Gothic2 with the D3D11 Renderer. I installed ReShade, after the game starts it says "Press Shift+F2 to open up settings".
Settings open up but I can't move the mouse cursor. It stays in the middle of the screen.
Using Win10, most recent version of Game, Renderer and ReShade.
I have the same issue in Layers of Fear where the mouse just trembles in the middle of the screen. I have to pause the game to use the GUI.
Don't remember which version I have installed for that game though....