[SOLVED] Reshade not launching

Hi,
I have been using Reshade for over 6 months and it was working well. Last week my PC had to be reset after a windows update cause continuous BSD's and since then I can not get Reshade to run at all. I use it mainly for The Sims 4. So far I have tried installing as Administrator in Reshade alone and with Admin in Reshade, Origin and Sims 4. I have tried switching from Sims 4 64 to 32, tried switching from direct3d9 to 10/11. I have checked and double checked installation is correct (SSD (E:) - Origin Games - The Sims4 - Game - Bin and that I have everything required to run it. I also tried installing it on Rise of the Tomb Raider but that didn't work either. Reshade has no problems installing it just doesn't run. I am now at a loss. Anyone got any ideas.

Thank you.

After playing around I finally worked out what the problem was.
Origin.
After Windows 10 reset itself, Origin had set my installs and saves on my C drive (M.2}. All my games files, folders etc are stored on my E {SSD} to keep free space on my C drive. Once I changed the path on Origin not only did Reshade pick it up during install but it started perfectly.
Not sure if it will help anyone but thought i'd post, it might help.