How to start with an effect enabled in Reshade 3.0

is there anything i can change in the settings to make it start with a shader enabled?

Yes just ticking the effect should start it enabled from then on.

If it's a preset the command in the ini file would be:

[GLOBAL]
Techniques=SMAA,

And that will make SMAA start enabled or what other effect or effects you want on.

The ini file itself with shader settings and these global settings is defined in reshade.ini or if that is not available it's [exename].ini

This line:
PresetFiles=C:\Program Files (x86)\ReShade\ReShade_Settings.ini

3.0? õ_Õ'

3.0 is in open beta since a while back, currently in the discussion thread I believe the latest download is for beta 3.0 #5 although only a few shaders are currently directly compatible with ReShade 3.0 at the moment and most if not all of them can be found via the ReShade Git repository.

github.com/crosire/reshade-shaders

EDIT: Latest version of 3.0 can be found in this post.
reshade.me/forum/general-discussion-2/19...sion?start=200#16319
(As of 3.0 ReShade only includes the core .dll files, shaders can be grabbed from that Git repository.)