Not really a game, but uses a DirectX realtime engine. I tried this out with iClone (version 6), and was able to get all the shaders to work. The DOF was my primary interest, as the DOF within iClone is not very pronounced. I couldn't get it to find a focus point though. All blurred, or none.

Tried the different settings in "Common", but to no avail.
So, iClone is an animation suite.