I played 400 hours of GTA V back when it wasn't awful on top of 650 hours of Battlefield 4 and 100 ish hours of Battlefield 1 using everything from SweetFX 1.5 to ReShade 3. I haven't recieved any complaints, and I don't know anyone who has. Basically you have a higher chance of being an astronaut.
-Note it's been well over half a year since I've played any of those. Only public multiplayer game I still play much at all is Smite, which I can't figure out how to inject ReShade into.