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Good catch, that button should not be visible in performance mode. Fixed in github.com/crosire/reshade/commit/cca66b...22274b048f79386f5cd3.

When pressing the floppy disk button 'Clean up and save current preset' while the Performance Mode is enabled, all shader settings are lost, because the preset file has been overwritten with only the header (and for some reason RadiantGI.fx, if installed). After disabling Performance Mode again, you will see that all variables are reset to their default values.

I am playing STALKER Anomaly and I am having the issue of the red error message "Unable to save current preset. Make sure you have write permissions to D:\MO2-Copy\overwrite\bin\ReShadePreset.ini" across the top of the screen. No matter what I do it does not work. I have unchecked "read-only" and have also checked it under security permissions and the error persists. I have even made sure to grant my user permsion to all of the files contents. The shaders will work if I enable them in game but I don't want to play with that on the screen.
  I have Mod Organizer 2 running my mods and a seperate Anomaly folder with the current reshade installed to it. Any help is appreciated. Thanks.

im on fs22 andi cant even found that file from x64

right click reshade.ini , properties - click on the Security tab then click on Edit.
- On the Permissions window click on the Add button to open the Select Users Group or Groups window.
- On the Select Users or Groups window you can enter the usernames i.e.,everyone.
- Then, click OK.
- Select Full Control by placing a check mark on “Allow”
- Apply the settings.

by default it is not read only and not hidden, so what you said isnt much help.
however:

you can take ownership of reshade.ini in the game's folder.
right click the file, properties, security tab. edit - add - change every one

In the properties window click on the Security tab then click on Edit.
- On the Permissions window click on the Add button to open the Select Users Group or Groups window.
- On the Select Users or Groups window you can enter the usernames i.e.,everyone.
- Then, click OK.
- Select Full Control by placing a check mark on “Allow”
- Apply the settings.

what noone tells you is pretty obvious if you have the know how.
find reshade.ini in the folder of the game you installed reshade for.
Right click properties, security tab click edit, and add full rights for everyone. you can also set ownership to everyone here, which will also solve your problems.

Ok so a lot of people haven't been able to figure this out for nearly years, and honestly I think we all just missed one little step that would solve all issues. When it says "Unable to save to preset" Or somewhere along the lines like that. 1.) You need to go to your game folder where you installed the game at. 2.) You have to find the .ini where it's trying to save your reshade preset at. 3.) You have to right click on the .ini file. 4.) You have to then click properties. 5.) Then near the bottom you'll see "Attributes" it will have the options "Read-only" and "Hidden". 6.) Then UNCHECK "Read-only". 7.) Last but not least click "Apply" and that's it you've fixed your Reshade preset error that annoys you 24/7. Hoped this helped .

I compiled the latest bleeding edge version of reshade today, and between my last build (July 26th) and now, an important behavior changed. Before, reshade would load from the exe location (e.g. reshade.ini is loaded from/saved to the exe folder, preset selector defaults to exe folder), but now it loads from the dll folder. The main problem with this behavior is with Vulkan games, as it means every vulkan game shares the same reshade.ini (in C:/Program Data/Reshade), rather than having their own reshade.ini in their exe folder. The other major case where this behavior could be problematic is when it is necessary to use an external injection tool to load reshade, such as with Genshin Impact (due to anticheat), and UWP games.

hello, i installed reshade today to gta 5
but everything i choose won't save and i have a message at the top of my screen saying:'' unable to save... make sure you have write permissions to Z:\Grand Theft Auto V\ReShadePreset.ini.''

the problem is, there is no ReShadePreset.ini. in that folder. 
how do i fix it? thank you if u try/if u can help me

Hi, I cannot open ReShade with the HOME key. I've seen other posts with people having the same problem as me, and they've changed the keybind and it works. However in the Reshade.ini file, I only get this:

[GENERAL]
EffectSearchPaths=.\reshade-shaders\Shaders,.\reshade-shaders\Shaders\qUINT,.\reshade-shaders\Shaders\PD80,.\reshade-shaders\Shaders\Depth3D,.\reshade-shaders\Shaders\AstrayFX,.\reshade-shaders\Shaders\OtisFX,.\reshade-shaders\Shaders\Daodan,.\reshade-shaders\Shaders\Fubax,.\reshade-shaders\Shaders\CorgiFX
PerformanceMode=0
PreprocessorDefinitions=RESHADE_DEPTH_LINEARIZATION_FAR_PLANE=1000.0,RESHADE_DEPTH_INPUT_IS_UPSIDE_DOWN=0,RESHADE_DEPTH_INPUT_IS_REVERSED=0,RESHADE_DEPTH_INPUT_IS_LOGARITHMIC=0
PresetPath=
TextureSearchPaths=.\reshade-shaders\Textures

[OVERLAY]
ShowClock=0
ShowFPS=1
TutorialProgress=0

[SCREENSHOT]
SavePath=

There's nothing here about keybinds. Am I missing something or is something wrong? If it helps the game specifically is Garry's Mod.

Open Reshade config file ReShade.ini find block [INPUT] and change value of
KeyOverlay=36,0,0,0 to key you want and save changes. Corresponding keycodes www.mods.com.au/budapi_docs/Virtual%20Key%20Codes.htm
For example, binding key L  to toggle ReshadeUI overlay
KeyOverlay=76,0,0,0

If your config misses that block just add it and change all values you need (main 3 here KeyOverlay, KeyScreenshot and KeyEffects):

[INPUT]
ForceShortcutModifiers=1
InputProcessing=2
KeyEffects=145,0,0,0
KeyNextPreset=0,0,0,0
KeyOverlay=36,0,0,0
KeyPerformanceMode=0,0,0,0
KeyPreviousPreset=0,0,0,0
KeyReload=0,0,0,0
KeyScreenshot=44,0,0,0

huntar wrote:

What should i do.
 

You should use the forum search function: reshade.me/forum/search?query=save%20pre...ildforums=1&catids=9
 

What should i do.I try to fix but not work. help pls