Turning certain effects off and on with hotkeys

I use a very heavy DoF that's just meant for screenshots, because of this I would like to be able to permanently turn it off and on by pressing button. I currently have it setup like this:
"#define DoF_ToggleKey VK_INSERT"
The problem with that is that it turns on again as soon as it recompiles the shaders, which happens everytime you swap between maps in Guild Wars 2. To avoid that I just turn it on and off manually in the config files, but that's a bit tedious.

#define DoF_ToggleKey 0x23 <---- I use the end key for DOF

Open \ReShade\McFX\DoF.h
Find line technique DoF_Tech
Change < bool enabled = RFX_Start_Enabled; ... > to < bool enabled = false; ... >