I installed ReShade into NieR Replicant ver.1.22474487139... yesterday, and after fiddling with the global preprocessor definitions, was able to get working depth. Today I attempted to install SpecialK to remove the cursor bug, and since then the depth has been broken. I've since completely uninstalled SpecialK and performed a clean reinstall of NieR, alongside ReShade, however the depth remains broken only with effects. I've attached some examples using SSR and DoF.
imgur.com/a/1EKEDMy
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