Depth buffer works, but only when a mouse button is held

In World of Warcraft client 3.3.5a, I am using depth buffers for rtgi shader and depth3d. Like the title says, I get depth effects but only when holding down either mouse button. I can sort of kludge it by using a mouse lock addon but it would be much better to just keep it on.I thought it might be the network detection thing, but I have built reshade from source and removed the check from runtime.cpp, unless there's somewhere else that also does a check.Any idea what's going on? The effect nearly halves my dps but I'd still love to be able to use it.

Edit: Have issue with both 5.6 and 5.7