I'm not a shader expert so I'm not sure how to describe or even what the problem is exactly so I will do my best to explain it. Basically I switch to a preset that has some sort of depth I believe, but then sometimes it constantly reloads it without me doing anything. Like it loads the preset, reloads it, or only reloads certain aspects of the preset so everything is different. Like out of focus, or no shadows etc. Is there a way to fix this? I only use it for FFXIV stuff and it seems to do it on all the presets that I can tell. Please and thank you for your help and/or time! I'll also list the preset I used to love using that's doing this, maybe that will help?
Use the ReShade build with full add-on support. The normal build you have installed disables depth access when it detects network activity (hence DOF/AO stop working randomly) to prevent exploitation, as a courtesy to anti-cheats (which is not relevant in FFXIV).