External Assistant for use in non-game application

I use Reshade with Poser Pro 2014 to enhance the realtime OpenGL viewport, but this isn't possible with 3.0, since hitting Shift+F2 does nothing in Poser (Reshade loads, but I can't change shaders without the menu). If/when there's time, could Mediator be updated to work with 3.0's shaders? Please

Unfortunately, it's not that simple, as some effects work quite well, and some do not, and there is no game that has the same OpenGL shader subset to test with. It would be like playing Final Fantasy 7 in order to improve one's skills at F1 racing games. I guess I'll keep using 2.

As an alternate request, is it possible to have newer shaders work in version 2?

You can edit Reshade settings without the UI, just manually edit the preset.ini file, or configure the preset using another game, like Marty said