No, as the waifu2x algorithm is for still images (the textures in games) and would be significantly too slow for a moving scene - even on a high end system, multiple frames of gametime would pass before Waifu2x could finish drawing a single actual frame. It works based on learning the patterns in the still image and deconstructing them so it can effectively draw them the same at a larger size.
What Dolphin supports is texture packs, which can be made with Waifu2x
Please Log in or Create an account to join the conversation.