Tried with a couple of freeware RAM disk software (ImDisk, SoftPerfect RAM Disk, ...) and it worked with all of them for me. Make sure the path you enter in the "IntermediateCachePath" config option does actually exist before ReShade is started (ReShade will not attempt to create it if it does not and will instead fall back to the default).
ReShade doesn't do anything particularly special to check if the path exists, so if it still fails with your RAM disk software that would indicate a bug in their implementation, rather than ReShade.
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