Just thought I'd report a small bug. This probably has something to do with the post-processing bloom in the game.
When Reshade is enabled, bloom is normal and not over-bloomed. When you toggle effects off after about a 2-3 second wait the bloom seems to go crazy and over-bloom the image dramatically. When you re-toggle effects. Bloom returns to normal.
My settings in game are all maxed out, might be linked to a setting.