First off, in all the other games that don't give me any problems, the new version is awesome. The in-game configurator makes my life so much easier.
On to my problem: 3.0.1 refuses to play nice with Mass Effect. It crashes every time when initializing the shaders, with a 0xC0000005 access violation and d3d9.dll being at the top of the call stack (according to the UE minidump, which I can upload somewhere if you want it).
As far as I remember, versions <3.0 worked just fine.
I've tried the usual stuff, like killing all overlays, disabling DEP and antivirus, running it without GeDoSaTo, rummaging in the INI files, changing install location, etcetera.
As soon as I rename d3d9.dll, it starts up just fine.