Not sure which OpenGL version it uses but minimum is a OpenGL 3.0 and recommended a OpenGL 4.0 compatible graphics card.
Last Reshade 2 version:
Game freezes on the loading screen. When pressing enter which starts the game it is possible to hear the in game sound and control the aircraft, just the screen is stuck.
Works without effects enabled, when an effect is enabled the game freezes. The sound and controls still work.
Disabling the effect doesn't fix the problem, after restarting with all effects disabled it works again.
When opening the reshade menu while the screen is stuck shows that the game window does not update, it looks like when old version of windows crashed and the settings window/overlay leaves behind a trail of overlapping copies.