I thought it was weird that Metro LLR keeps crashing when I try to open it with ReShade but not otherwise. I've installed the dxgi.dll and forcing the game to render with DX11 through user.cfg. The funny thing is, Metro 2033 (non-redux) works perfectly and there are many people who have gotten ReShade working with Last Light Redux with no errors whatsoever.
Metro 2033 Redux also is really picky sometimes.
For some reason I can use just MasterEffect with it, but it crashes immediately if SweetFX is chained.
It is a "slim" version of SweetFX, with only lumasharpen and dither, it works with every single game I'd tried, minus Metro 2033 Redux. Funny thing, if I enable "#include "Sweet.fx" while ingame, it works (I can see lumasharpen in action) but crash after a while.
I'm downloading LL Redux right now, maybe I'll come back with a proper feedback.
Meanwhile, try MasterEffect instead of SweetFX if you haven't.
EDIT: It is working fine with me also.
RadeonPRO was preventing the game form booting with Reshade, though.
Make sure to disable every software that you use for monitoring stuff.