Prepar3d v4.3 Unable to change settings

Hello everyone,
lastly I installed Reshade in Prepar3d V4.3 and it's works great but without the control to change the settings in the in-game UI.

The mouse does not seem to change anything.

Thank you very much for your help

It is via Keybinds and there is an article in the forums about it and in the readme I learned it the hard way after 4 reinstalls of reshade