I've just reinstalled Reshade for the Sims 4, and Shift+F2 doesn't open the menu.
The bar does start at the beginning, so Reshade is open.
My ReShade.ini does not have a KeyMenu value.. this is all it has.
I have the exact same problem. I know it loads in successfully and when I press scroll lock I can see the chosen preset turn on and off, but I cannot access the in game menu no matter how much I press shift+f2 or the home button... please help.. Ive tried reinstalling it, but am honestly lost for what else to do. (Witcher 3 btw)
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