I noticed this while playing the flighting build and is even persisting on release build... when any particle or glowing effects (in-game post processing?) are visible on screen, a 2nd smaller depth buffer (1/4 of full image) appears to overlap on top-left corner, and this breaks any and all depth based shaders. No way of disabling any graphical settings in-game either as the options are simply unavailable.
I hope this issue can be resolved as the game is ideal for running shaders such as Marty's RTGI and SSR.
Edit: One person (Digital Dreams) has resorted to using an outdated version of ReShade (4.4) to avoid this problem, which has something about a "clear depth buffer before stencil" in DX tab.