Never install any game into system folders that the installer suggests by default. Always create a new custom folder to the root of your drive, ie. "C:\Games". That will prevent problems with countless of games and Reshade will have no problems caused by writing permissions.
right click reshade.ini , properties - click on the Security tab then click on Edit.
- On the Permissions window click on the Add button to open the Select Users Group or Groups window.
- On the Select Users or Groups window you can enter the usernames i.e.,everyone.
- Then, click OK.
- Select Full Control by placing a check mark on “Allow”
- Apply the settings.