Yup . I tested several times. I use the framework version with performance tweak (makes it faster than original ReShade SweetFX). All I had enabled was SMAA, FXAA, and LumaSharpen. Even if I left only SMAA enabled, the game framerate would decrease barely, but I would get semi-frequent stutters in Borderless Mode. Borderless Mode has a tendency to cause stutters on its own in some games, but in Witcher 3 it doesn't as long as ReShade SweetFX is not used. I didn't just set everything to 0 in SweetFX config to get rid of stutters, but I had to remove DXGI.dll, ReShade.FX, and ReShade folder to get back to smooth gameplay.
Has anyone else experienced a similar problem? Should I ask in Framework sub-section of the forum?
I am not sure that is it. My framerate does not vary that much in any game, but in Witcher 3, I just occasional mini-stutter when the game just stops for a few milliseconds. I think it may be a dropped frame or something like that. It could be just due to Borderless Window mode...