Says it right there: You don't have writing permissions to files in C:\Program Files by default. Either give your user those, or move the preset to a different location, or run the game as administrator.
The following user(s) said Thank You: ghostlyy.demon
what noone tells you is pretty obvious if you have the know how.
find reshade.ini in the folder of the game you installed reshade for.
Right click properties, security tab click edit, and add full rights for everyone. you can also set ownership to everyone here, which will also solve your problems.
The following user(s) said Thank You: Ellassbugs, ghostlyy.demon
that was happening to me so i decided to just delete reshade. i deleted all the files but that error message is still there at the top at all times. pls help what do i do???