Edit: After I rolled back my graphical drivers from the latest 378.49 to the previous 376.33, the game runs with all Reshade-versions without any issues. So I think the main problem is the latest Nvidia-driver 378.49. Hope this helps you figuring out what's causing the crash.
Since the new Watch_Dogs 2 patch (v.109.154.1001103) the game crashes on startup with the following message:
Here is the Event Viewer error information: Faulting application name: WatchDogs2.exe, version: 0.1.0.1, time stamp: 0x58611cf7
Faulting module name: dxgi.dll, version: 22.214.171.124, time stamp: 0x563dd991
Exception code: 0xc0000005
Fault offset: 0x00000000000377f3
Faulting process id: 0x2b8
Faulting application start time: 0x01d2770af410bd21
Faulting application path: G:\!Games!\Ubisoft\Ubisoft Game Launcher\games\WATCH_DOGS2\bin\WatchDogs2.exe
Faulting module path: G:\!Games!\Ubisoft\Ubisoft Game Launcher\games\WATCH_DOGS2\bin\dxgi.dll
Report Id: 33d40a7e-e2fe-11e6-a5cd-4ccc6a2d7f46
I tried turning off the Anti-Cheat program using the following command in the short-cut: -eac_launcher, but the game still crashes. After removing Reshade's .dll file (dxgi.dll or dx3d11.dll) the game starts up with no issues, with or without the Anti-Cheat program. I also tried all previous Reshade-versions: from 126.96.36.1993 to 3.0.6, all with the same crash/issue. The game looks washed out without Reshade
Thanks in advance for your time looking into this issue.
Windows 7 Ultimate 64bit / Windows 10 Pro (latest build)
Intel Core i7 6800K
I got a similar error with 378.49
I tried using Reshade versions 0.19.2, 1.1.0, 2.0.3, 3.0, 3.0.6 and got crash WD2 at splash screen stage. This happened after update Nvidia Driver from 376.60 to 378.49.
Remove dxgi/d3d11 dll fix this ofc....