I can not open the reshade menu when I have presse

Why tell me the solution plz i use this in gta V

... Press Shift + F2?

i have pressed it but can not open

do you have other solution ?

Do you get a small grey window at the top left saying that ReShade is loading? If it is missing, ReShade hasn't been properly installed in the first place, and we would first have to fix that.

Or maybe you don't press the keys at the same time..? First press Shift, and while you are pressing it, add F2.